Deadpool has had an epiphany and realizes that the reason he and all the other costumed characters are trapped in an endless cycle of killing and resurrection is that they are all fictional characters and the only way to end the cycle is to kill EVERYONE. He temporarily spares Mad Thinker, Leader, Egghead and some of the other genius super-villains to work for him. Mad Thinker explains that they have come up with a theory based on his idea that they are all fictional characters; if he travels through the Nexus of All Realities to the realm of the Classics and murders those characters, comic heroes and villains will have nothing to be based upon and thus disappear. Deadpool enters the Nexus after leaving HERBIEs of Death to execute the super-villains and murders Don Quixote, Moby Dick, and prepares to match wits with Sherlock Holmes.