The Phantom Stranger vol.2 #14

"The Man with No Heart!" - Answering the call of Broderick Rune, the Phantom Stranger finds himself knocked out with a powerful gas. Rune then has his men perform a heart transplant, using the Stranger's very own heart. However, when his goons go to dump the body, they are shocked to find that the blanket they were carrying the Stranger's body is empty, and that the Stranger is very much alive.
The Stranger then begins to haunt and stalk Rune everywhere he goes causing him to panic and flee to his second estate. There the haunting continues, and so they try mystical means of ridding themselves of the Phantom Stranger, this also doesn't work. Finally, the Stranger appears and chases Rune out into a field where he dies of a heart attack. When his aides can finally get to him, they are shocked to find that Rune doesn't have a heart in his body.

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