Exercise Physiology #1

The first edition of Exercise Physiology: Human BioenergeticsanditsApplications was a departure in terms of focus on human bioenergetics in describing muscle performance in terms of energy transduction at cellular levels. Our approach came out of the the (early 1970s) burgeoning field of exercise biochemistry and use of various techniques such as electron microscopy and mitochondrial respirometry. In the second and third editions we utilized findings of human metabolism based on use of isotope tracers to study metabolism. That technique resulted in articulation of the Crossover Conceptand proving of the Lactate Shuttle Hypothesis in human subjects. In the fourth edition of Exercise Physiology this theme has been retained, but the approach has become increasingly mechanistic due to many developments, including the use of molecular and cellular biology and isotope tracer technology in the field. Now, in the fifth edition we continue in traditions of the first four editions, but adjust and revise as the ever-increasing appreciation of exercise physiology increases, as reflected in the Exercise in Medicine, and publication of the 2018 Physical Activity guidelines and the application of exercise physiology to develop countermeasures for space travel.

Medicina e Saúde