De la Cruz has revamped traditional vampire lore in this story featuring a group of attractive, privileged Manhattan teens who attend a prestigious private school. Schuyler Van Alen, 15, the last of the line in a distinguished family, is being raised by her distant and forbidding grandmother. Schuyler, her friend Oliver, and their new friend Dylan are treated like outsiders by the clique of popular, athletic, and beautiful teens made up of Mimi Force, her twin brother, and her best friend. What they have in common is the fact that they are all Blue Bloods, or vampires. They don't realize that they aren't normal until they reach age 15. Then the symptoms manifest themselves and they begin to crave raw meat, have nightmares about events in history, and get prominent blue veins in their arms. Their immortality and way of life are threatened after Blue Blood teens start getting murdered by a splinter group called the Silver Bloods.